Perhaps a more powerful round like the 10mmmight be able to break critical parts of the skeleton causing an attacker to fall. I say perhaps because I am not sure what it takes to snap a femur or shatter a pelvis.
I do keep a 12 ga pump shotgun around the house with the tube loaded with #4 buck. At close range probably 3 or 4 center of mass hits will stop most people.
I remember a Story I was told second hand by a Filipina. A friend of hers at the university had been a soldier and they had juar, this was in late 60's or early 70's, burned a muslim village using the village gas pump to set the fire. A man came out of the smoke with a big kris and a soldier in front of him emptied his M16 into the attacker. The amok attacker did not stop and split the head of the first soldier. The soldier that told the story said he turned and ran. Not really clear if the attacker was hit, but he likely was.
